What are the risks of total knee replacement surgery?

Total knee replacement surgery is one of the most successful orthopedic procedures in the world. For people suffering from severe knee arthritis, deformity, or long-standing knee pain, it can restore mobility, eliminate pain, and significantly improve quality of life. Modern medical technology, advanced surgical techniques, robotic precision, and improved implant designs have made knee replacement safer and more predictable than ever.

 

However, like any major surgery, Total Knee Replacement (TKR) also carries certain risks and potential complications. Understanding these risks is extremely important so patients can make informed decisions, prepare properly, and follow postoperative care carefully to reduce complications.

This page explains in simple language:

  • Possible risks of knee replacement

  • How common they are

  • Why they happen

  • How doctors minimize them

  • How you can reduce risks

  • When to seek medical help

The aim is not to frighten patients, but to provide clear, honest, and reassuring information so that you feel confident and prepared.


Why Understanding Risks Is Important

A knee replacement consultation is not just about planning surgery — it is about education, clarity, and transparency.

Understanding risks helps patients:

  • Reduce fear and anxiety

  • Know what to realistically expect

  • Prepare mentally and physically

  • Follow postoperative instructions properly

  • Identify warning signs early

  • Improve recovery outcomes

A well-informed patient always recovers better.


How Safe Is Total Knee Replacement Surgery?

Total knee replacement is considered one of the safest orthopedic surgeries globally. Success rates are very high, with more than 90–95% of patients experiencing:

  • Significant pain relief

  • Better mobility

  • Improved walking ability

  • Enhanced daily functioning

  • Long-lasting results (many implants last 15–25+ years)

Complications are uncommon, and most can be managed effectively when identified early and treated by experienced orthopedic teams.


Factors That Influence Risk

Not every patient has the same risk level. Your individual risk depends on:

  • Age

  • General medical health

  • Diabetes or hypertension control

  • Weight / BMI

  • Bone quality

  • Muscle strength

  • Smoking / alcohol history

  • Previous knee surgeries

  • Immunity and healing capacity

  • Activity level

Your orthopedic surgeon carefully evaluates all these factors before recommending surgery.


Common Risks of Total Knee Replacement Surgery


1️⃣ Infection

What is it?

Infection can occur around the surgical incision or deep inside the replaced joint.

How common is it?

Very rare — less than 1–2% of cases globally.

Symptoms of infection

  • Redness around wound

  • Persistent swelling

  • High fever

  • Pus discharge

  • Increasing pain

  • Bad wound smell

Prevention

  • Sterile surgical techniques

  • Antibiotics before & after surgery

  • Proper wound care

  • Blood sugar control in diabetic patients

Treatment

Mild infections → antibiotics
Severe infections → rarely require additional procedures


2️⃣ Blood Clots (Deep Vein Thrombosis)

Why does it happen?

Reduced mobility after surgery can slow blood flow, causing clot formation.

Symptoms

  • Swelling in calves

  • Pain or tenderness

  • Warmth or redness in leg

Serious risk

If clot travels to lungs (Pulmonary Embolism) — medical emergency.

Prevention

  • Blood-thinning medicines

  • Compression stockings

  • Early walking after surgery

  • Leg exercises

  • Hydration

With proper precautions, risk significantly reduces.


3️⃣ Implant Loosening or Wear Over Time

Why does it happen?

Like any artificial device, knee implants may gradually wear over many years.

More likely in:

  • Very active patients

  • Heavy weight patients

  • High-impact activities

Symptoms

  • Increasing knee pain

  • Instability

  • Reduced movement

Prevention

  • High-quality modern implants

  • Proper surgical alignment

  • Controlled activity lifestyle

Many implants now last 15–25 years or more.


4️⃣ Stiffness or Reduced Knee Movement

What causes stiffness?

  • Scar tissue formation

  • Weak muscles

  • Delayed physiotherapy

  • Improper rehabilitation

Prevention

  • Early movement

  • Regular physiotherapy

  • Stretching & strengthening exercises

Treatment

In rare severe cases, manipulation under anesthesia may be required.


5️⃣ Persistent Pain

Most patients experience strong relief, but a small percentage may have ongoing discomfort.

Reasons may include

  • Soft tissue pain

  • Scar tissue

  • Minor implant irritation

  • Nerve sensitivity

  • Rare complications

Good news

Most pain improves with time, exercises, and proper rehabilitation.


6️⃣ Nerve or Blood Vessel Injury (Rare)

Extremely uncommon due to modern precision surgery.

When occurs:

  • Temporary numbness or weakness

  • Usually improves over time

Highly skilled surgeons + careful surgical planning minimize risk.


7️⃣ Bone Fracture During or After Surgery

Rare but possible:

  • During implant placement

  • Due to falls post-surgery

  • Due to weak bones

Managed with fixation or minor additional procedures if needed.


8️⃣ Allergic Reaction

Some patients may react to:

  • Implant metals (rare)

  • Anesthesia medicines

Doctors screen allergy history before surgery.


9️⃣ Implant Misalignment or Technical Errors

This is why choosing an experienced knee replacement surgeon matters.

Modern advancements like:

  • Computer navigation

  • Robotic knee replacement

  • Advanced planning software

greatly improve accuracy.


🔟 General Surgical & Anesthesia Risks

As with any major surgery:

  • Bleeding

  • Reaction to anesthesia

  • Heart or breathing issues (rare)

Pre-operative check-ups minimize this risk.

How Doctors Reduce Risks

Experienced orthopedic surgeons follow strict safety protocols:

  • Comprehensive pre-operative health evaluation

  • Blood tests & cardiac clearance

  • Optimizing diabetes & blood pressure

  • Strict sterile surgery environment

  • Advanced anesthesia monitoring

  • Precision surgical techniques

  • High-quality implants

  • Early mobilization

  • Physiotherapy support

  • Regular follow-ups

 

This is why treatment under a skilled specialist provides reassurance.

Frequently Asked Questions

1. Is total knee replacement surgery safe?

Total knee replacement is considered a very safe and successful procedure worldwide, but like any major surgery, it carries a few risks.

2. What are the most common risks of total knee replacement surgery?

Common risks include infection, blood clots, stiffness, implant wear, persistent pain, and anesthesia-related complications.

3. How common is infection after knee replacement?

Infection is rare and occurs in less than 1–2% of cases. Proper sterilization, antibiotics, and wound care greatly reduce this risk.

4. Can blood clots occur after knee replacement?

Yes, blood clots (Deep Vein Thrombosis) can occur due to reduced mobility, but doctors prevent this using medicines, stockings, and early walking.

5. Can the knee implant loosen or fail over time?

Yes, implants may wear or loosen over many years, especially in very active or overweight patients, but modern implants are highly durable.

6. Is stiffness common after total knee replacement?

Some patients may experience stiffness if physiotherapy is not followed properly, but exercises and rehabilitation help prevent this.

7. Can pain continue even after knee replacement surgery?

Most patients experience excellent pain relief, but a small percentage may have ongoing discomfort that can usually be managed.

8. Are nerve or blood vessel injuries possible?

These complications are extremely rare due to modern surgical techniques and experienced surgeons.

9. What general surgical risks should I know about?

General risks include bleeding, anesthesia reactions, or heart complications, which are minimized through proper medical evaluation.

10. How can I reduce the risk of complications after knee replacement?

Follow your doctor’s instructions, attend physiotherapy, control diabetes and blood pressure, avoid smoking, and report any unusual symptoms early.

Table of Contents

Introduction

Total knee replacement surgery is a procedure in which damaged knee joint surfaces are replaced with artificial components to relieve pain and improve movement. Total Knee Replacement

Candidates

Total knee replacement is suitable for individuals with severe knee pain, stiffness, and joint damage that no longer improves with medications, injections, or physiotherapy. Candidates

Cost

The cost of total knee replacement varies based on implant type, surgical technique, hospital stay, and rehabilitation requirements, so an individualized evaluation is essential. Cost

Consultation

During a consultation, the orthopedic surgeon evaluates symptoms, knee function, X-ray/MRI reports, medical fitness, lifestyle needs, and treatment history to decide whether surgery is necessary — Consultation.

Questions to Ask

Patients should ask about the necessity of surgery, procedure details, implant type, benefits, risks, hospital stay, recovery time, rehabilitation, and long-term expectations — Questions to Ask.

Risks and Safety

Total knee replacement is generally safe and highly successful, though complications like infection, bleeding, blood clots, stiffness, or implant wear may rarely occur, which can be minimized with expert care — Risks and Safety.

Preparation

Preparation includes medical evaluation, medication review, pre-surgery exercises, home planning, and understanding the procedure and recovery process. Preparation

Steps

The procedure involves removing damaged joint surfaces, placing artificial components, restoring alignment, and closing the joint with postoperative care. Steps

Recovery

Recovery typically includes pain control, early mobilization, physiotherapy, gradual strength improvement, and regular follow-up visits. Recovery

Results

Most patients experience significant pain relief, improved knee function, better mobility, and enhanced quality of daily activities. Results

Before and after

Before-and-after results often show reduced pain, improved joint alignment, increased walking ability, and better overall knee movement. Before and after

Choosing the right surgeon

Choosing the right surgeon involves assessing experience, specialization in joint replacement, patient outcomes, and clear communication. Choosing the right surgeon